GOOD HEALTH AND WELL-BEING

Certain organisms in nature harbor toxins in their bodies for their survival and predation. Fragaceatoxin C (FraC), a pore-forming toxin from sea anemones, binds to lipid membranes and injures cells b [...]

がん性疼痛は進行期のがん患者のほとんどが経験する耐え難い困難のひとつであるが、その発症メカニズムについては複合的な要因が絡み合うため解明が難航している。本研究では独自に作成したがん性疼痛モデルマウスを用い、がん性疼痛が概日変動を示すこと、さらにその概日リズム制御に関わる因子としてCancer-Evoked Pain Factor (CEPF：仮称)を同定した。そこで、CEPFによるより詳細ながん性 [...]

Peroxisomes are organelles that exist in almost all eukaryotic cells and are responsible for diverse and important metabolic functions, including β-oxidation of very long-chain fatty acids. However, t [...]

Chemically modified peptides and proteins, which contain organic groups between cystine disulfides, have recently attracted considerable interest, because their modifications can impart various functi [...]

Inkjet printing technology is recognized as a significant breakthrough in fabricating gas sensing systems. In addition, desktop inkjet printers make this technology affordable, potentially allowing ev [...]

Covalent inhibitors have become the hotspot of pharmaceutical science recently as the strong inhibitory effect and longer retention time attributed to the warhead forming a covalent bond with active a [...]

This study focuses on the increase of type 2 innate lymphoid cells (ILC2s) in the brain and periventricular tissues of ASD model mice. We aim to clarify how ILC2s affect ASD-like behaviors and brain p [...]

I am conducting research on a drug delivery system (DDS) that selectively delivers pollen antigens to Langerhans cells to induce immune tolerance, aiming to establish a fundamental therapy for pollino [...]

Development of cell-specific targeting methods based on modification of lipid specificity of pore-forming toxins.

がん性疼痛の概日変動メカニズムを基盤にした新規治療法の開発

Molecular mechanism analysis of transmembrane machinery in peroxisomal matrix protein transport

Rhodium-catalyzed Insertion Reactions to Unprotected Peptide Disulfides

Molecularly Imprinted Chemiresistive Gas Sensors Based on Fully Inkjet Printing Technology

Development of novel covalent inhibitors based on selective acylation of lysine residue

analysis of ILC2 in autism spectrum disorder

Induction of Immune Tolerance Using Langerhans Cell-Targeting Peptides and Its Application to Non-Invasive Pollinosis Therapy

“Future-Creation (MIRAI)” Course Kyushu University SPRING program