GOOD HEALTH AND WELL-BEING

1. 研究背景と目的/Research Background and Purpose Microglia are known to have three major subtypes: ramified type, M1 type, and M2 type. Ramified type is called quiescent microglia, while M1 and M2 types are [...]

Intracellular trafficking is a route responsible for the transport of molecules within the cell and widely conserved in eukaryotes. Endocytosis is a pathway which uptakes membrane proteins and extrace [...]

Oral lichen planus (OLP) is a chronic inflammatory disease that forms reticular or patchy white lesions in the oral mucosa, sometimes accompanied by erosions and ulcers. Our laboratory focuses on the [...]

Tissue engineering with stem cell has been developed for years. Current trends indicate that mesenchymal stem cells (MSCs) for regeneration work by secreting signaling protein, cytokine, and gene expr [...]

Physicochemical Basis for Spontaneous Smooth Folding of Protein Molecules: Thermodynamic and Kinetic Analyses at the Amino Acid Residue Level of a Foldable Polypeptide Using NMR

Department of Systems Life Sciences, Graduate School of Systems Life Sciences

The antimicrobial peptide nukacin ISK-1 is in an equilibrium between two states of different topologies in solution. We determined the equilibrium constant K and exchange rate constants k on a per-res [...]

The skin constitutes a complex and dynamic epithelial-immune microenvironment (EIME), maintaining tissue homeostasis (Nat Immunol. 19, 1286–1298, 2018). Under imbalances of cross-talk between epiderma [...]

This study aims to investigate the effect of oral care on oral health-related quality of life in older people who receives nursing care at home. Previous studies in older people requiring long-term ca [...]

　Vancomycin (VCM) is frequently used in the treatment of Methicillin-resistant staphylococcus aureus (MRSA) due to its efficacy. However, VCM is clinically problematic because it is prone to acute nep [...]

Relationship between microglia-mediated dendritic spine formation and schizophrenia.

Analysis of molecular mechanism of AAA ATPase AipA involved in endocytosis in Aspergillus oryzae

Elucidation of network mechanism between epithelium and dendritic cells in oral lichen planus

Development of Complex Coacervate for Cell Microencapsulation

Physicochemical Basis for Spontaneous Smooth Folding of Protein Molecules: Thermodynamic and Kinetic Analyses at the Amino Acid Residue Level of a Foldable Polypeptide Using NMR

The role of cholesterol sulfate in homeostasis of the epithelial-immune microenvironment

Examining changes in oral health awareness and oral health behaviors before and after an oral health care intervention

Chronopharmacological studies of vancomycin-induced nephrotoxicity focused on macrophages.

“Future-Creation (MIRAI)” Course Kyushu University SPRING program