GOOD HEALTH AND WELL-BEING

This research aims to elucidate the mechanism of durotaxis and derive the equation of motion for cells. Cells generate forces spontaneously and move through interactions with the substrate, but the re [...]

The progress of regenerative medicine has been remarkable. Regenerative techniques using undifferentiated stem cells such as embryonic stem cells and iPS cells are attracting attention. Even in the fi [...]

Cancer-associated fibroblasts (CAFs) occupy the majority of a tumor’s microenvironment in Pancreatic Cancer. These cells contribute to the aggressive behavior of cancer cells, and confer resistance to [...]

近年、エクソン領域やイントロン領域の変異が新規スプライス部位を形成し、転写産物に異常なエクソンが挿入されて、疾患を引き起こすという報告がある。しかし、このスプライス部位形成変異（splice-site-creating mutation: SCM）は、遺伝性疾患の原因として散発的に報告されているだけで、実際に疾患に関与するSCMがどの程度存在するかについては明らかにされていない。そこで、私は、バイ [...]

Even the simplest of living cells are complex biological machines. This makes figuring out the physical principles behind many of the processes that occur inside them incredibly difficult. To solve th [...]

Analysis of Inhalation Exposure to Microplastics in Indoor Environments based on the Adsorption Model of SVOCs and Numerical Respiratory Tract Model

Department of Interdisciplinary Engineering Science, Interdisciplinary Graduate School of Engineering Sciences

In recent years, the issue of microplastics in the marine environment has emerged as a societal concern in the context of environmental problems. On the other hand, indoors, where it is estimated that [...]

Homologous recombination (HR) is a reaction that repairs DNA double-strand breaks (DSBs) using homologous sequences. This process is crucially dependent on the strand exchange reaction and DNA synthes [...]

Cellular heterogeneity plays an important role in tissue organization, for example, regulating HSC stem cell balance enables the immune system to rejuvenate (Ross et al., Nature 2024). In the mouse ta [...]

Derivation of the equation of motion for cells through the elucidation of the mechanism of durotaxis

Elucidation of the mechanism of ameloblast differentiation and polarization regulation by cell junction factors

Research on the role of CAFs population and its impact on PDAC progression.

遺伝性疾患の原因となるスプライス部位形成変異の疾患横断的探索

Study of intracellular active gels by artificial cell reconstitution: from cellular dynamics to multicellular order

Analysis of Inhalation Exposure to Microplastics in Indoor Environments based on the Adsorption Model of SVOCs and Numerical Respiratory Tract Model

The functional interface between strand exchange and DNA synthesis in homologous recombination

Heterogeneous alterations in epidermal stem cell dynamics in response to inflammation

“Future-Creation (MIRAI)” Course Kyushu University SPRING program