We have investigated into a role of SPOCK1, an extracellular proteoglycan discovered as an inducer of epithelial-mesenchymal transition (EMT), in drug-induced gingival overgrowth (DIGO). It has been f [...]
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The fetal liver is the tissue in which hematopoiesis, angiogenesis, and hepatopoiesis occur. Sinusoidal endothelial cells are vascular endothelial cells that make up the sinusoidal wall, the liverR [...]
The cell surface of pathogenic fungi is composed of glycolipids such as glucosylceramide (GlcCer) and ergosterylglucoside (EG), and their metabolism is involved in the acquisition of infectivity and c [...]
Diabetic peripheral neuropathic pain arise from the accumulation of metabolic factors (sorbitol) in nerve cells caused by hyperglycemia. Therefore, it is essential to suppress of development and prog [...]
It is estimated that about 13 million people in Japan suffer from chronic kidney disease (CKD), and diabetic kidney disease (DKD), which is caused by diabetes mellitus, accounts for about 40% of the t [...]
Recent studies have shown rapid progress in image manipulation, which enables an attacker to manipulate the important area of a medical image (e.g., CT or MRI) or modify the disease attribute revealed [...]
Transfer RNA (tRNA) is the representative noncoding RNA involved in protein translation, and precursor tRNA undergoes complex maturation processes to become the functional tRNA. Among these maturation [...]
In this study, I try to create MCM8-9 inhibitors, which are promising as novel anti-cancer agents. DNA double-strand break (DSB) is one of the severe forms of DNA damages in cells. Some DSBs are repai [...]