GOOD HEALTH AND WELL-BEING

Phospholipids that constitute cell membranes are easily oxidized due to the presence of polyunsaturated fatty acids within molecules, leading to the formation of a wide variety of oxidized phospholipi [...]

Memory defines who we are as humans. Memory allows us to obtain information and skills and to recall past events. Scientists have been diving into understanding memory’s mechanisms and how memory was [...]

Palmoplantar pustulosis (PPP) is a chronic inflammatory skin disease characterized by recurrent pruritic pustules on the palms and soles, significantly impairing patients’ quality of life. While chron [...]

Nucleic acid delivery technologies such as lipid nanoparticles (LNPs) have spread worldwide as mRNA vaccine formulations for new coronavirus infections, and many researchers are still actively engaged [...]

Macrophages play an important role as the starting point of cancer immunity by phagocytosing cancer cells and causing activation of immune cells such as T cells and B cells. Our laboratory has previou [...]

DNA, the genetic material, is damaged by endogenous as well as exogenous sources such as base alkylating chemicals. Some alkylating reagents produce O-6-methylguanine (O6mG), which induces cell death, [...]

The purpose of this research is to create novel sialidase inhibitors. We found that slightly modified sialic acids exhibited much stronger sialidase inhibitory activity than known inhibitors. This fin [...]

I study the spectrum of Schrödinger operators. It is known that the temporal behavior of a quantum system can be characterized by the classification of the spectrum, with point spectrum corresponding [...]

Elucidation of the Novel Functions of Oxidized Phospholipids Focused on Protein Modification

The differences in the neural circuit pathways during fear memory acquisition and retrieval

Investigation of T Cell–Driven Immune Mechanisms in Palmoplantar Pustulosis and the Potential for Drug Repurposing

Pharmacokinetic analysis and cancer immunotherapy applications of lipid nanoparticle formulations using newly synthesized lipids.

Effects of novel phagocytosis-related enzymes in cancer immunity

In vitro analysis of mismatch-repair dependent processing of alkylated bases

Creation of new sialidase inhibitor based on a new molecular design concept

Spectral analysis of discrete Schrödinger operators with singular continuous spectrum

“Future-Creation (MIRAI)” Course Kyushu University SPRING program