GOOD HEALTH AND WELL-BEING

T-box riboswitch regulates gene expression by monitoring the aminoacylation state of tRNAs. A ribozyme derived from a modified T-box riboswitch, Tx2.1, can aminoacylate tRNAs with a noncanonical amino [...]

Glioblastoma (GBM) is a highly aggressive brain tumor with a 5-year survival rate of approximately 10%. Its poor prognosis is partly attributed to cancer stem cells, which contribute to therapy resist [...]

哺乳類ではたった一つの受精卵から個体が形成される。このように一つの細胞から一個体を形成できる能力を全能性といい、その性質を有する細胞を全能性細胞という。したがって全能性細胞は生命の源であり、その分子基盤を理解することは「生命とは何か」に対する知見をもたらす。本研究では着床前初期発生過程の細胞核を用いたプロテオーム解析から全能性制御に関与する要素の同定を目指す。

The intestinal tract contains more than 1000 species and 100 trillion bacteria, which are constantly exposed to foreign microorganisms and food-derived antigens. Therefore, the intestinal tract has a [...]

Propofol is an intravenous anesthetic widely used for general anesthesia and sedation in intensive care, utilized in over 90% of scheduled surgeries in adults. However, high-dose, long-term administra [...]

DNA mismatch repair (MMR) is a mutation avoidance system that post-replicatively corrects nucleotide misincorporation errors. However, eukaryotic genomes are wrapped around histones to be assembled in [...]

In childcare institutions and special-needs schools and support facilities, there are common issues. 1) graphics for visual aids are not systematic and it is left to childcare workers and teachers to [...]

Animal cells such as Chinese hamster ovary (CHO) cells have been utilized as producer host cells for the production of pharmaceutical proteins. However, the culturing of these animal cells requires la [...]

Mechanistic Study and Applications of tRNA Aminoacylation by T-box riboswitch-based ribozyme

Elucidation of mechanism of malignancy in glioblastoma by TIMELESS

プロテオーム解析によるマウス初期胚の全能性基盤要素の同定

Elucidation of the Regulatory Mechanisms Involving PRIP in the Gut-Brain Interaction

Comprehensive Analysis of the Pathogenesis of Propofol Infusion Syndrome

In vitro reconstitution of the eukaryotic DNA mismatch repair in the context of chromatin

Symbol representation function level and pictogram comprehension in preschool and autistic children

Development of pharmaceutical protein production technology by transgenic chickens

“Future-Creation (MIRAI)” Course Kyushu University SPRING program