Image Inpainting for Human Face Wearing a Mask Department of Systems Life Sciences, Graduate School of Systems Life Sciences In today’s world situation, after so many twists and turns of covid-19, we may find that this storm will not stop easily. Therefore, masks will become a necessity of people’s lives for a l [...]
Mechanistic Study and Applications of tRNA Aminoacylation by T-box riboswitch-based ribozyme Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences T-box riboswitch regulates gene expression by monitoring the aminoacylation state of tRNAs. A ribozyme derived from a modified T-box riboswitch, Tx2.1, can aminoacylate tRNAs with a noncanonical amino [...]
Elucidation of mechanism of malignancy in glioblastoma by TIMELESS Department of Medicinal Sciences, Graduate School of Pharmaceutical Sciences Glioblastoma (GBM) is a highly aggressive brain tumor with a 5-year survival rate of approximately 10%. Its poor prognosis is partly attributed to cancer stem cells, which contribute to therapy resist [...]
プロテオーム解析によるマウス初期胚の全能性基盤要素の同定 Department of Systems Life Sciences, Graduate School of Systems Life Sciences 哺乳類ではたった一つの受精卵から個体が形成される。このように一つの細胞から一個体を形成できる能力を全能性といい、その性質を有する細胞を全能性細胞という。したがって全能性細胞は生命の源であり、その分子基盤を理解することは「生命とは何か」に対する知見をもたらす。本研究では着床前初期発生過程の細胞核を用いたプロテオーム解析から全能性制御に関与する要素の同定を目指す。
Elucidation of the Regulatory Mechanisms Involving PRIP in the Gut-Brain Interaction Department of Dental Science, Graduate School of Dental Science The intestinal tract contains more than 1000 species and 100 trillion bacteria, which are constantly exposed to foreign microorganisms and food-derived antigens. Therefore, the intestinal tract has a [...]
Comprehensive Analysis of the Pathogenesis of Propofol Infusion Syndrome Department of Medical Sciences, Graduate School of Medical Sciences Propofol is an intravenous anesthetic widely used for general anesthesia and sedation in intensive care, utilized in over 90% of scheduled surgeries in adults. However, high-dose, long-term administra [...]
In vitro reconstitution of the eukaryotic DNA mismatch repair in the context of chromatin Department of Systems Life Sciences, Graduate School of Systems Life Sciences DNA mismatch repair (MMR) is a mutation avoidance system that post-replicatively corrects nucleotide misincorporation errors. However, eukaryotic genomes are wrapped around histones to be assembled in [...]
Symbol representation function level and pictogram comprehension in preschool and autistic children Department of Design, Graduate School of Design In childcare institutions and special-needs schools and support facilities, there are common issues. 1) graphics for visual aids are not systematic and it is left to childcare workers and teachers to [...]
