Function of Pot1a in the maintenance of normal hematopoietic stem cells and acute myeloid leukemia niche.
- Department of Medical Sciences, Graduate School of Medical Sciences
Hematopoietic stem cells (HSCs) localize to microenvironments (niche) in the bone marrow and maintain stemness by interacting with niche cells. Furthermore, Leukemic stem cells (LSCs) are essential [...]
Research keywords
- 間葉系幹細胞
- 造血幹細胞
- ニッチ
- シェルタリン因子
- 急性骨髄性白血病