GOOD HEALTH AND WELL-BEING

In recent years, the development of new drugs has been difficult due to the cost of research and the time required for their commercialization. On the other hand, highly accurate drug discovery metho [...]

We have investigated into a role of SPOCK1, an extracellular proteoglycan discovered as an inducer of epithelial-mesenchymal transition (EMT), in drug-induced gingival overgrowth (DIGO). It has been f [...]

The fetal liver is the tissue in which hematopoiesis, angiogenesis, and hepatopoiesis occur. Sinusoidal endothelial cells are vascular endothelial cells that make up the sinusoidal wall, the liver&#82 [...]

The cell surface of pathogenic fungi is composed of glycolipids such as glucosylceramide (GlcCer) and ergosterylglucoside (EG), and their metabolism is involved in the acquisition of infectivity and c [...]

Diabetic peripheral neuropathic pain arise from the accumulation of metabolic factors (sorbitol) in nerve cells caused by hyperglycemia. Therefore, it is essential to suppress of development and prog [...]

It is estimated that about 13 million people in Japan suffer from chronic kidney disease (CKD), and diabetic kidney disease (DKD), which is caused by diabetes mellitus, accounts for about 40% of the t [...]

Recent studies have shown rapid progress in image manipulation, which enables an attacker to manipulate the important area of a medical image (e.g., CT or MRI) or modify the disease attribute revealed [...]

Transfer RNA (tRNA) is the representative noncoding RNA involved in protein translation, and precursor tRNA undergoes complex maturation processes to become the functional tRNA. Among these maturation [...]

Development of high-throughput drug discovery method using quantum chemical calculations

Effects of Spock1 on the progression of periodontal disease

Mechanisms of sinusoidal endothelial cell development and regeneration

Development of novel glycolipid-type probes based on enzymatic reaction mechanisms and tracking glycolipid degradation

Chronopharmacological study of SGLT2 inhibitor in diabetic peripheral neuropathy model mice

The molecular mechanism of association between periodontal inflammation and diabetic kidney diseases

Medical data forgery detection framework for the future AI era

Structure analysis of the 3'-terminal maturation enzyme RNase Z in eukaryotic precursor tRNA

“Future-Creation (MIRAI)” Course Kyushu University SPRING program