Physicochemical Basis for Spontaneous Smooth Folding of Protein Molecules: Thermodynamic and Kinetic Analyses at the Amino Acid Residue Level of a Foldable Polypeptide Using NMR
- Department of Systems Life Sciences, Graduate School of Systems Life Sciences
The antimicrobial peptide nukacin ISK-1 is in an equilibrium between two states of different topologies in solution. We determined the equilibrium constant K and exchange rate constants k on a per-res [...]
Research keywords
- NMR
- protein folding
- self-consistency principle
- linear free energy relationship